White matter changes and poststroke dementia

Dement Geriatr Cogn Disord. 1998 Jul:9 Suppl 1:25-9. doi: 10.1159/000051186.

Abstract

Stroke patients are more likely to have white matter changes than age- and sex-matched controls. White matter changes are associated with an increased risk of dementia occurring after stroke: they often indicate a higher risk of stroke recurrence and they may lead to slight cognitive impairment. Besides white matter changes, vascular lesions of the brain and associated Alzheimer pathology, the summation of 2 or 3 of these mechanisms may lead to dementia in stroke patients even when each type of lesion is not severe enough to induce dementia by its own.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain / pathology*
  • Cerebrovascular Disorders / complications*
  • Cerebrovascular Disorders / pathology*
  • Dementia / etiology*
  • Dementia / pathology*
  • Humans