Development of a high-throughput in vitro bioassay to assess potencies of progestagenic compounds using chinese hamster ovary cells stably transfected with the human progesterone receptor and a luciferase reporter system

Anal Biochem. 1998 Aug 1;261(2):222-4. doi: 10.1006/abio.1998.2681.
No abstract available

MeSH terms

  • Animals
  • Biological Assay / instrumentation
  • Biological Assay / methods*
  • Biological Assay / standards
  • CHO Cells
  • Cricetinae
  • Genes, Reporter
  • Humans
  • Luciferases / genetics*
  • Miniaturization
  • Pregnenediones / pharmacology
  • Progesterone Congeners / pharmacology*
  • Receptors, Progesterone / genetics*
  • Transfection

Substances

  • Pregnenediones
  • Progesterone Congeners
  • Receptors, Progesterone
  • 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione
  • Luciferases