Neurodevelopmental outcome after open fetal surgery

D L Gibbs; R E Piecuch; J L Graf; C H Leonard; J A Farrell; M R Harrison

doi:10.1016/s0022-3468(98)90162-2

Neurodevelopmental outcome after open fetal surgery

J Pediatr Surg. 1998 Aug;33(8):1254-6. doi: 10.1016/s0022-3468(98)90162-2.

Authors

D L Gibbs¹, R E Piecuch, J L Graf, C H Leonard, J A Farrell, M R Harrison

Affiliation

¹ Fetal Treatment Center and the Department of Surgery, The University of California, San Francisco 94143-0570, USA.

PMID: 9721998
DOI: 10.1016/s0022-3468(98)90162-2

Abstract

Purpose: This study examined the neurological and age-appropriate developmental outcomes of 11 children who underwent open fetal surgery.

Results: Nine children have normal neurological outcomes, and nine have normal development.

Conclusion: Intensive postnatal care, intracranial hemorrhage, and requirement for prolonged respiratory support were associated with a worse neurological and developmental prognosis.

MeSH terms

Central Nervous System Diseases / diagnosis
Central Nervous System Diseases / etiology
Cystic Adenomatoid Malformation of Lung, Congenital / surgery*
Female
Fetal Diseases / diagnosis
Fetal Diseases / mortality
Fetal Diseases / surgery*
Hernia, Diaphragmatic / surgery*
Hernias, Diaphragmatic, Congenital
Humans
Infant
Infant, Newborn
Male
Neurologic Examination
Pregnancy
Pregnancy Outcome
Prognosis
Surgical Procedures, Operative / adverse effects
Surgical Procedures, Operative / methods
Survival Rate
Treatment Outcome