Molecular events involved in differentiation of thyroid follicular cells

Mol Cell Endocrinol. 1998 May 25;140(1-2):37-43. doi: 10.1016/s0303-7207(98)00027-6.

Abstract

Organogenesis is a complex event, often dependent on inductive tissue interactions, that ultimately promote expression and activation of a combinatorial sequence of transcription factors which are involved in controlling migration, growth and differentiation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Cell Transformation, Neoplastic
  • DNA-Binding Proteins / physiology
  • Forkhead Transcription Factors
  • Gene Expression Regulation, Developmental
  • Homeodomain Proteins / physiology
  • Humans
  • Nuclear Proteins / physiology
  • PAX8 Transcription Factor
  • Paired Box Transcription Factors
  • Thyroid Gland / cytology
  • Thyroid Gland / growth & development*
  • Thyroid Gland / metabolism
  • Thyroid Neoplasms / genetics
  • Thyroid Neoplasms / pathology
  • Thyroid Nuclear Factor 1
  • Trans-Activators / physiology
  • Transcription Factors / genetics
  • Transcription Factors / physiology*

Substances

  • DNA-Binding Proteins
  • Forkhead Transcription Factors
  • Homeodomain Proteins
  • Nuclear Proteins
  • PAX8 Transcription Factor
  • PAX8 protein, human
  • Paired Box Transcription Factors
  • Thyroid Nuclear Factor 1
  • Trans-Activators
  • Transcription Factors

Grants and funding