A novel missense mutation in the homeodomain of the hepatocyte nuclear factor-1alpha/maturity-onset diabetes of the young 3 in a Japanese early-onset type 2 diabetic patient and time-course of glucose-stimulated insulin secretion

Diabetes Care. 1998 Sep;21(9):1569-71. doi: 10.2337/diacare.21.9.1569.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Blood Glucose / metabolism*
  • DNA-Binding Proteins / genetics*
  • Diabetes Mellitus, Type 2 / genetics*
  • Female
  • Glucose Tolerance Test
  • Hepatocyte Nuclear Factor 1
  • Hepatocyte Nuclear Factor 1-alpha
  • Hepatocyte Nuclear Factor 1-beta
  • Humans
  • Insulin / metabolism*
  • Insulin Secretion
  • Male
  • Middle Aged
  • Mutation, Missense*
  • Nuclear Proteins*
  • Time Factors
  • Transcription Factors / genetics*

Substances

  • Blood Glucose
  • DNA-Binding Proteins
  • HNF1A protein, human
  • HNF1B protein, human
  • Hepatocyte Nuclear Factor 1-alpha
  • Insulin
  • Nuclear Proteins
  • Transcription Factors
  • Hepatocyte Nuclear Factor 1
  • Hepatocyte Nuclear Factor 1-beta