Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents

Antimicrob Agents Chemother. 1998 Sep;42(9):2446-8. doi: 10.1128/AAC.42.9.2446.

Abstract

Fifty-two percent of stool specimens collected from 1,200 high-risk patients were colonized with yeasts, primarily Candida albicans (53. 6%) and Candida glabrata (35.7%). Susceptibilities to all antifungal agents tested, including LY303366, were similar to those reported previously for Candida species isolated from blood.

MeSH terms

  • Anidulafungin
  • Antifungal Agents / pharmacology*
  • Candida / drug effects*
  • Digestive System / microbiology*
  • Echinocandins
  • Humans
  • Microbial Sensitivity Tests
  • Peptides, Cyclic / pharmacology*
  • Risk

Substances

  • Antifungal Agents
  • Echinocandins
  • Peptides, Cyclic
  • Anidulafungin