Discovery of a potent and selective alpha 1A antagonist. Utilization of a rapid screening method to obtain pharmacokinetic parameters

Pharm Biotechnol. 1998:11:423-43.

Authors

K K Adkison¹, K A Halm, J E Shaffer, D Drewry, A K Sinhababu, J Berman

Affiliation

¹ Glaxo Wellcome Research and Development, Research Triangle Park, North Carolina 27709, USA.

PMID: 9760690

No abstract available

Publication types

Review

MeSH terms

Adrenergic alpha-1 Receptor Antagonists*
Adrenergic alpha-Antagonists / analysis
Adrenergic alpha-Antagonists / pharmacokinetics*
Adrenergic alpha-Antagonists / therapeutic use
Animals
Chromatography, Liquid
Humans
Mass Spectrometry
Structure-Activity Relationship

Substances

Adrenergic alpha-1 Receptor Antagonists
Adrenergic alpha-Antagonists