Abstract
A series of N-(4-methoxy, 4-fluoro, 4-trifluoromethyl and 4-nitrobenzoyl)-L-amino acids was synthesized and their inhibitory activity towards bovine lens aldose reductase (ALR2) was tested.
MeSH terms
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Aldehyde Reductase / antagonists & inhibitors*
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Amino Acids / chemical synthesis*
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Amino Acids / chemistry
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Amino Acids / pharmacology
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Animals
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Cattle
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Enzyme Inhibitors / chemical synthesis*
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / pharmacology
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Lens, Crystalline / enzymology
Substances
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Amino Acids
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Enzyme Inhibitors
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Aldehyde Reductase