Granulocytic sarcoma presented as a reactivation of chronic myeloid leukemia after allogenic marrow transplantation

Sao Paulo Med J. 1998 Mar-Apr;116(2):1689-91. doi: 10.1590/s1516-31801998000200009.

Abstract

The authors report the case of a chronic myeloid leukemia (CML) patient submitted to allogenic bone marrow transplantation, who had probably never entered complete remission. The disease was reactivated as a granulocytic sarcoma, next to a platinum plate installed to correct a tibia fracture 11 years earlier. Its final event was a myeloid Ph1 + blastic crisis that was unsuccessfully treated with high doses of sc interferon and citarabine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use
  • Blast Crisis / drug therapy
  • Bone Marrow Transplantation / adverse effects*
  • Cytarabine / therapeutic use
  • Fatal Outcome
  • Female
  • Humans
  • Interferons / therapeutic use
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / etiology
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy*
  • Leukemia, Myeloid / etiology
  • Recurrence

Substances

  • Antineoplastic Agents
  • Cytarabine
  • Interferons