Abstract
Seven newly diagnosed patients with Devic's neuromyelitis optica were treated with long-term prednisone and azathioprine, and were followed every 2 months for at least 18 months. Their Expanded Disability Status Scale score improved significantly (mean at baseline, 9; mean at 18 months, 3; p < 0.005), and no relapses occurred for more than 18 months. Multicenter controlled studies are needed to prove the efficacy of this therapeutic regimen.
Publication types
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Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Anti-Inflammatory Agents / administration & dosage*
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Azathioprine / administration & dosage*
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Disability Evaluation
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Female
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Humans
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Immunosuppressive Agents / administration & dosage*
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Middle Aged
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Neuromyelitis Optica / drug therapy*
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Neuromyelitis Optica / rehabilitation
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Prednisone / administration & dosage*
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Prospective Studies
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Recurrence
Substances
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Anti-Inflammatory Agents
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Immunosuppressive Agents
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Azathioprine
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Prednisone