Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts

Anal Biochem. 1998 Nov 1;264(1):129-32. doi: 10.1006/abio.1998.2833.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5-Methylcytosine
  • Artifacts
  • CpG Islands*
  • Cytosine / analogs & derivatives
  • Cytosine / metabolism*
  • DNA Methylation*
  • Sequence Analysis, DNA*
  • Sulfites / chemistry

Substances

  • Sulfites
  • 5-Methylcytosine
  • Cytosine