Infective endocarditis is a severe disease observed frequently in cardiologic centers. The importance of echocardiography in the diagnosis, the morphological criteria of vegetations, abscesses and periaortic complications were analyzed. The use of transesophageal echocardiography in patients with surgical indication is assessed. The significance of clinical symptoms of infective endocarditis in the echocardiographic interpretation must be always taken into consideration.