Vesicle formation: dynamic dynamin lives up to its name

Curr Biol. 1998 Nov 5;8(22):R792-4. doi: 10.1016/s0960-9822(07)00501-5.

Abstract

The GTP-binding protein dynamin was initially thought to be required for just the final stages of clathrin-dependent vesicle formation, but recent results indicate that it can actually catalyse many of the essential steps in the vesiculation pathway.

Publication types

  • Review

MeSH terms

  • Animals
  • Coated Vesicles / physiology*
  • Dynamins
  • GTP Phosphohydrolases / genetics
  • GTP Phosphohydrolases / physiology*
  • GTP-Binding Proteins / genetics
  • GTP-Binding Proteins / physiology*
  • Nerve Tissue Proteins / metabolism
  • Synaptic Vesicles / physiology*

Substances

  • Nerve Tissue Proteins
  • amphiphysin
  • GTP Phosphohydrolases
  • GTP-Binding Proteins
  • Dynamins