No evidence for linkage of a novel CA repeat polymorphism for apoptosis antigen 1 (APO-1 or fas) with type I diabetes in a Caucasian population

Hum Hered. 1998 Nov-Dec;48(6):343-5. doi: 10.1159/000022827.

Abstract

A novel microsatellite marker was found within 48.5 kb of the Fas gene. The observed heterozygosity in 160 healthy unrelated controls was 0.78. There was no evidence of linkage to type I diabetes mellitus in 120 diabetic children using the transmission disequilibrium test.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Child
  • DNA Primers
  • Diabetes Mellitus, Type 1 / genetics*
  • Gene Frequency
  • Genetic Linkage*
  • Heterozygote
  • Humans
  • Microsatellite Repeats*
  • Polymorphism, Genetic*
  • White People / genetics*
  • fas Receptor / genetics*

Substances

  • DNA Primers
  • fas Receptor