bcr-abl rearrangement in adult T-lineage acute lymphoblastic leukemia

Haematologica. 1998 Sep;83(9):856-7.

Abstract

The bcr-abl rearrangement in T-lineage ALL has been rarely described. In the last three years we studied all new patients with ALL at diagnosis by cytogenetic and molecular analysis. Three out of eleven T-lineage ALL patients presented the rearrangement and only one was Philadelphia positive.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Fatal Outcome
  • Fusion Proteins, bcr-abl / analysis*
  • Genes, abl*
  • Humans
  • Karyotyping
  • Leukemia-Lymphoma, Adult T-Cell / genetics*
  • Leukemia-Lymphoma, Adult T-Cell / pathology
  • Male
  • Middle Aged
  • Philadelphia Chromosome
  • Prognosis

Substances

  • Fusion Proteins, bcr-abl