Abstract
A patient with HIV infection was successfully treated for pulmonary tuberculosis, but pulmonary inflammation and lymphadenitis worsened dramatically after subsequent combination antiretroviral therapy. As this relapse coincided with development of a strong delayed-type hypersensitivity response to tuberculin and improved after treatment with the anti-inflammatory agent oxpentifylline, it was probably caused by restoration of pathogen-specific cellular immunity.
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy*
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AIDS-Related Opportunistic Infections / immunology
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Adult
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Anti-HIV Agents / administration & dosage
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Anti-HIV Agents / adverse effects*
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Drug Hypersensitivity / immunology*
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Drug Therapy, Combination
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Humans
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Hypersensitivity, Delayed / chemically induced*
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Hypersensitivity, Delayed / immunology
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Immunity, Cellular / drug effects
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Immunity, Cellular / immunology
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Male
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Mycobacterium tuberculosis / immunology*
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Risk Factors
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Tuberculin Test*
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Tuberculosis, Pulmonary / drug therapy*
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Tuberculosis, Pulmonary / immunology