Verotoxin-producing Escherichia coli (VTEC) and eae-positive non-VTEC in 1-30-days-old diarrhoeic dairy calves

Vet Microbiol. 1998 Oct;63(2-4):239-48. doi: 10.1016/s0378-1135(98)00218-1.

Abstract

Faecal samples from 221, 1-30-days-old, diarrhoeic dairy calves were screened for the presence of verotoxin-producing Escherichia coli (VTEC) and eae-positive non-VTEC. Calves were grouped according to their age (1-7, 8-14, 15-21 and 22-30 days) and analyses of prevalences were done by Mantel-Haenzsel chi 2-test for trend. VTEC and eae-positive non-VTEC were detected in 20 (9.0%) and 18 (8.1%) of the diarrhoeic calves, respectively. A significant age-associated increase in the prevalence of VTEC (p = 0.0001), but not in the prevalence of eae-positive non-VTEC (p = 0.381), was found. Significant differences in VTEC prevalence were found between the age-group 22-30 days and in all other age-groups. 43 (5.0%) of the 861 E. coli isolates from the 221 diarrhoeic calves were VTEC, and 30 (69.8%) of these strains produced VT1 only. More than one-half of the VTEC strains (55.8%) were positive for the eae gene and all these eae-positive VTEC strains produced VT1 only. A high percentage (76.7%) of VTEC strains belonged to E. coli serogroups (O4, O26, O39, O91, O113, O128 and O145) associated with haemorrhagic colitis and haemolytic uraemic syndrome in humans. 51 (5.9%) of the E. coli strains studied were eae-positive non-VTEC and the serogroups most prevalent among these strains were O4, O14, O26 and O123. Only four of the eae-positive strains were also espB-positive by hybridization with a probe from a human EPEC isolate and none of these strains produced VT.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesins, Bacterial*
  • Age Factors
  • Animals
  • Animals, Newborn
  • Bacterial Outer Membrane Proteins / genetics*
  • Bacterial Toxins / biosynthesis*
  • Carrier Proteins*
  • Cattle
  • Cattle Diseases / microbiology*
  • Chlorocebus aethiops
  • Diarrhea / microbiology
  • Diarrhea / veterinary*
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification*
  • Escherichia coli / physiology
  • Escherichia coli Infections / microbiology
  • Escherichia coli Infections / veterinary*
  • Escherichia coli Proteins*
  • Feces / microbiology
  • Female
  • Humans
  • Polymerase Chain Reaction
  • Shiga Toxin 1
  • Vero Cells

Substances

  • Adhesins, Bacterial
  • Bacterial Outer Membrane Proteins
  • Bacterial Toxins
  • Carrier Proteins
  • EaeB protein, E coli
  • Escherichia coli Proteins
  • Shiga Toxin 1
  • eaeA protein, E coli