Intrafamilial association of pericentric inversion of chromosome 9, inv (9)(p11-q21), and rapid cycling bipolar disorder

F McCandless; I Jones; K Harper; N Craddock

doi:10.1097/00041444-199808040-00011

Intrafamilial association of pericentric inversion of chromosome 9, inv (9)(p11-q21), and rapid cycling bipolar disorder

Psychiatr Genet. 1998 Winter;8(4):259-62. doi: 10.1097/00041444-199808040-00011.

Authors

F McCandless¹, I Jones, K Harper, N Craddock

Affiliation

¹ Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK.

PMID: 9861647
DOI: 10.1097/00041444-199808040-00011

Abstract

Association of a chromosome aberration and psychiatric disorder can be useful in highlighting a genomic region that can be profitably explored further using positional cloning. We report the case of a father and daughter both of whom have bipolar disorder II and a pericentric inversion of chromosome 9.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Bipolar Disorder / complications
Bipolar Disorder / genetics*
Child
Chromosome Inversion*
Chromosomes, Human, Pair 9 / genetics
Chromosomes, Human, Pair 9 / ultrastructure*
Depression, Postpartum / etiology
Depressive Disorder, Major / genetics
Dyslexia
Female
Humans
Intellectual Disability / complications
Male
Pedigree