Differentiating human from animal isolates of Cryptosporidium parvum

Emerg Infect Dis. 1998 Oct-Dec;4(4):681-5. doi: 10.3201/eid0404.980424.

Abstract

We analyzed 92 Cryptosporidium parvum isolates from humans and animals by a polymerase chain reaction/restriction fragment length polymorphism method based on the thrombospondin-related anonymous protein 2 gene sequence. Used as a molecular marker, this method can differentiate between the two genotypes of C. parvum and elucidate the transmission of infection to humans.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / microbiology*
  • Cryptosporidiosis / epidemiology
  • Cryptosporidiosis / parasitology*
  • Cryptosporidiosis / veterinary*
  • Cryptosporidium parvum / classification*
  • Cryptosporidium parvum / genetics
  • Cryptosporidium parvum / isolation & purification
  • Disease Outbreaks*
  • Genotype
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • Protozoan Proteins / genetics*
  • Sequence Analysis, DNA

Substances

  • Protozoan Proteins
  • thrombospondin-related adhesive protein, protozoan