[Parkinson's disease and anosmia in monozygotic twin sisters (author's transl)]

J Genet Hum. 1976 Jun;24(2):113-7.
[Article in French]

Abstract

Monozygotic twin sisters developed Parkinson's disease and anosmia at the age of 39. The disease was kept under control and regressed with L. Dopa. Two families with the same association had been previously reported. An anomaly of the metabolism of dopamine, genetically determined, is probably responsible for these disorders.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Diseases in Twins*
  • Dopamine / metabolism
  • Female
  • Humans
  • Levodopa / therapeutic use
  • Olfaction Disorders / complications
  • Olfaction Disorders / genetics*
  • Parkinson Disease / complications
  • Parkinson Disease / drug therapy
  • Parkinson Disease / genetics*
  • Pedigree
  • Pregnancy
  • Twins, Monozygotic

Substances

  • Levodopa
  • Dopamine