Rhinacanthin-Q, a naphthoquinone from Rhinacanthus nasutus and its biological activity

Phytochemistry. 1998 Dec;49(7):2001-3. doi: 10.1016/s0031-9422(98)00425-7.

Abstract

The continuing investigation of the root of Rhinacanthus nasutus afforded a 1,4-naphthoquinone ester, rhinacanthin-Q, accompanied by twenty-four known compounds. The structure was elucidated on the basis of spectroscopic analyses. The cytotoxicity and antiplatelet effect of this compound was also discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • KB Cells / drug effects
  • Naphthoquinones / chemistry
  • Naphthoquinones / isolation & purification*
  • Naphthoquinones / pharmacology*
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification*
  • Plant Extracts / pharmacology*
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Platelet Aggregation / drug effects
  • Platelet Aggregation Inhibitors / pharmacology

Substances

  • Naphthoquinones
  • Plant Extracts
  • Platelet Aggregation Inhibitors
  • rhinacanthin Q