[Conditioned reflex activity in rats after chronic antenatal gamma irradiation in association with mercazolyl]

Radiats Biol Radioecol. 1998 Nov-Dec;38(6):874-82.
[Article in Russian]

Abstract

The purpose of investigation is the study of combined influence of gamma-radiation (137Cs, 1.25 Gy during 20 days) and mercazolyl (20 mg/100 ml drinkable water) in utero on the intellectual state of rats in the postnatal ontogenesis. It was shown, that antenatal separate influence both of gamma-radiation and mercazolyl induced the delay of intellectual development in 2 and 7 months age. The combined influence of these factors induced essential increase observed effect. There is a party of the conditioned reflex activity in 7 month age.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Age Factors
  • Animals
  • Antithyroid Agents / pharmacology*
  • Conditioning, Classical / drug effects*
  • Conditioning, Classical / radiation effects*
  • Female
  • Fetus / drug effects*
  • Fetus / radiation effects*
  • Gamma Rays*
  • Male
  • Methimazole / pharmacology*
  • Pregnancy
  • Rats
  • Rats, Wistar
  • Time Factors

Substances

  • Antithyroid Agents
  • Methimazole