Right ventricular impairment in patients with chronic respiratory failure on home oxygen therapy--non-invasive assessment using a new Doppler index

J Int Med Res. 1998 Oct-Nov;26(5):239-47. doi: 10.1177/030006059802600503.

Abstract

We evaluated the usefulness of the newly defined Doppler index combining systolic and diastolic myocardial performance, in assessing right-heart dysfunction in 29 patients with chronic respiratory failure caused by old tuberculosis who were on 24-h home oxygen therapy. We measured tricuspid inflow velocity, right-ventricular outflow velocity, late/early diastolic peak velocities (A/E), the ratio between pre-ejection period and ejection time (PEP/ET), and the new index of systolic and diastolic myocardial performance (SDMP) calculated as (isovolumetric contraction time + isovolumetric relaxation time)/ejection time. The calculated A/E, PEP/ET and SDMP in our patients were significantly higher than those in age-matched healthy subjects (n = 37, mean age 67 +/- 8 years). There was no overlap in the SDMP index between healthy subjects and patients and the index was not influenced by heart rate. Our results suggest that SDMP index is a better marker than A/E and PEP/ET for the assessment of right-ventricular impairment.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Chronic Disease
  • Echocardiography, Doppler
  • Female
  • Heart / physiopathology
  • Heart Function Tests
  • Home Care Services*
  • Humans
  • Male
  • Middle Aged
  • Oxygen Inhalation Therapy*
  • Respiratory Insufficiency / complications*
  • Respiratory Insufficiency / physiopathology
  • Respiratory Insufficiency / therapy*
  • Tuberculosis, Pulmonary / complications
  • Ventricular Dysfunction, Right / complications*
  • Ventricular Dysfunction, Right / physiopathology