Abstract
The occurrence of leukemic pleural effusion is a rare complication in chronic lymphocytic leukemia and has not been reported in B-cell prolymphocytic leukemia (B-PLL). We report a case of pleural effusion revealing a B-PLL. The diagnosis was made on the cytological and immunological characteristics of cells in the blood and pleural effusion. This patient was treated with fludarabine and was in complete remission after three courses. This observation may have clinical implications for the use of new adenoside nucleotide analogues in symptomatic B-PLL.
MeSH terms
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Aged
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Antibodies
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Antigens, CD20
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Antineoplastic Agents / therapeutic use
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Humans
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Immunohistochemistry
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Leukemia, B-Cell / complications*
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Leukemia, Prolymphocytic / complications*
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Leukemia, Prolymphocytic / diagnosis
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Leukemia, Prolymphocytic / drug therapy
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Male
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Pleural Effusion, Malignant / diagnosis
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Pleural Effusion, Malignant / drug therapy
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Pleural Effusion, Malignant / etiology*
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Remission Induction
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Tomography Scanners, X-Ray Computed
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Vidarabine / analogs & derivatives
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Vidarabine / therapeutic use
Substances
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Antibodies
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Antigens, CD20
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Antineoplastic Agents
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Vidarabine
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fludarabine