Residues in transmembrane regions III and VI contribute to the 5-ht6 receptor ligand binding site

Ann N Y Acad Sci. 1998 Dec 15:861:242-3. doi: 10.1111/j.1749-6632.1998.tb10200.x.
No abstract available

MeSH terms

  • Amino Acid Sequence
  • Amino Acid Substitution
  • Aspartic Acid
  • Binding Sites
  • Binding, Competitive
  • Cell Line
  • Cell Membrane / metabolism
  • Conserved Sequence
  • Cyclic AMP / metabolism
  • Humans
  • Hydrogen Bonding
  • Leucine
  • Ligands
  • Lysergic Acid Diethylamide / metabolism
  • Mutagenesis, Site-Directed
  • Receptors, Serotonin / chemistry*
  • Receptors, Serotonin / metabolism*
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / metabolism
  • Serine
  • Serotonin / pharmacology
  • Transfection

Substances

  • Ligands
  • Receptors, Serotonin
  • Recombinant Proteins
  • serotonin 6 receptor
  • Aspartic Acid
  • Serotonin
  • Serine
  • Lysergic Acid Diethylamide
  • Cyclic AMP
  • Leucine