Milhous WK - Search Results

1

8-Aminoquinolines active against blood stage Plasmodium falciparum in vitro inhibit hematin polymerization.

Vennerstrom JL, Nuzum EO, Miller RE, Dorn A, Gerena L, Dande PA, Ellis WY, Ridley RG, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. Antimicrob Agents Chemother. 1999 Mar;43(3):598-602. doi: 10.1128/AAC.43.3.598. Antimicrob Agents Chemother. 1999. PMID: 10049273 Free PMC article.

2

Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.

Vennerstrom JL, Ellis WY, Ager AL Jr, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 May 29;35(11):2129-34. doi: 10.1021/jm00089a025. J Med Chem. 1992. PMID: 1597862

3

Bisquinolines. 2. Antimalarial N,N-bis(7-chloroquinolin-4-yl)heteroalkanediamines.

Vennerstrom JL, Ager AL Jr, Dorn A, Andersen SL, Gerena L, Ridley RG, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1998 Oct 22;41(22):4360-4. doi: 10.1021/jm9803828. J Med Chem. 1998. PMID: 9784111

4

Fluoxetine hydrochloride enhances in vitro susceptibility to chloroquine in resistant Plasmodium falciparum.

Gerena L, Bass GT Sr, Kyle DE, Oduola AM, Milhous WK, Martin RK. Gerena L, et al. Among authors: milhous wk. Antimicrob Agents Chemother. 1992 Dec;36(12):2761-5. doi: 10.1128/AAC.36.12.2761. Antimicrob Agents Chemother. 1992. PMID: 1482144 Free PMC article.

5

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.

Vennerstrom JL, Fu HN, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 Aug 7;35(16):3023-7. doi: 10.1021/jm00094a015. J Med Chem. 1992. PMID: 1501229

6

Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum.

Karle JM, Karle IL, Gerena L, Milhous WK. Karle JM, et al. Among authors: milhous wk. Antimicrob Agents Chemother. 1992 Jul;36(7):1538-44. doi: 10.1128/AAC.36.7.1538. Antimicrob Agents Chemother. 1992. PMID: 1510452 Free PMC article.

7

In vitro activity of bisquinoline WR268,668 against African clones and isolates of Plasmodium falciparum.

Basco LK, Andersen SL, Milhous WK, Le Bras J, Vennerstrom JL. Basco LK, et al. Among authors: milhous wk. Am J Trop Med Hyg. 1994 Feb;50(2):200-5. doi: 10.4269/ajtmh.1994.50.200. Am J Trop Med Hyg. 1994. PMID: 8116813

8

Synthesis and antimalarial activity of sixteen dispiro-1,2,4, 5-tetraoxanes: alkyl-substituted 7,8,15,16-tetraoxadispiro[5.2.5. 2]hexadecanes.

Vennerstrom JL, Dong Y, Andersen SL, Ager AL Jr, Fu H, Miller RE, Wesche DL, Kyle DE, Gerena L, Walters SM, Wood JK, Edwards G, Holme AD, McLean WG, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 2000 Jul 13;43(14):2753-8. doi: 10.1021/jm0000766. J Med Chem. 2000. PMID: 10893313

9

In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones.

Gutteridge CE, Hoffman MM, Bhattacharjee AK, Milhous WK, Gerena L. Gutteridge CE, et al. Among authors: milhous wk. Bioorg Med Chem Lett. 2011 Jan 15;21(2):786-9. doi: 10.1016/j.bmcl.2010.11.099. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21168330

10

Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents.

Karle JM, Olmeda R, Gerena L, Milhous WK. Karle JM, et al. Among authors: milhous wk. Exp Parasitol. 1993 Jun;76(4):345-51. doi: 10.1006/expr.1993.1042. Exp Parasitol. 1993. PMID: 8513873

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