Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor.
Goalstone ML, Leitner JW, Wall K, Dolgonos L, Rother KI, Accili D, Draznin B.
Goalstone ML, et al. Among authors: draznin b.
J Biol Chem. 1998 Sep 11;273(37):23892-6. doi: 10.1074/jbc.273.37.23892.
J Biol Chem. 1998.
PMID: 9727002
Free article.
We have previously demonstrated that insulin activates farnesyltransferase (FTase) and augments the amounts of farnesylated p21 (Goalstone, M. L., and Draznin, B. (1996) J. Biol. Chem. 271, 27585-27589). We postulated that this aspect of insulin action might explain …
We have previously demonstrated that insulin activates farnesyltransferase (FTase) and augments the amounts of farnesylated p21 (Goalstone, …