Lombó F - Search Results

1

Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.

Prado L, Lombó F, Braña AF, Méndez C, Rohr J, Salas JA. Prado L, et al. Among authors: lombo f. Mol Gen Genet. 1999 Mar;261(2):216-25. doi: 10.1007/s004380050960. Mol Gen Genet. 1999. PMID: 10102355

2

Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.

Lombó F, Blanco G, Fernández E, Méndez C, Salas JA. Lombó F, et al. Gene. 1996 Jun 12;172(1):87-91. doi: 10.1016/0378-1119(96)00029-7. Gene. 1996. PMID: 8654997

3

An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.

Fernández E, Lombó F, Méndez C, Salas JA. Fernández E, et al. Among authors: lombo f. Mol Gen Genet. 1996 Jul 26;251(6):692-8. doi: 10.1007/BF02174118. Mol Gen Genet. 1996. PMID: 8757400

4

Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.

Lombó F, Siems K, Braña AF, Méndez C, Bindseil K, Salas JA. Lombó F, et al. J Bacteriol. 1997 May;179(10):3354-7. doi: 10.1128/jb.179.10.3354-3357.1997. J Bacteriol. 1997. PMID: 9150235 Free PMC article.

5

The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.

Lombó F, Braña AF, Méndez C, Salas JA. Lombó F, et al. J Bacteriol. 1999 Jan;181(2):642-7. doi: 10.1128/JB.181.2.642-647.1999. J Bacteriol. 1999. PMID: 9882681 Free PMC article.

6

The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.

Lombó F, Künzel E, Prado L, Braña AF, Bindseil KU, Frevert J, Bearden D, Méndez C, Salas JA, Rohr J. Lombó F, et al. Angew Chem Int Ed Engl. 2000 Feb;39(4):796-799. doi: 10.1002/(sici)1521-3773(20000218)39:4<796::aid-anie796>3.0.co;2-n. Angew Chem Int Ed Engl. 2000. PMID: 10760873 No abstract available.

7

The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.

González A, Remsing LL, Lombó F, Fernández MJ, Prado L, Braña AF, Künzel E, Rohr J, Méndez C, Salas JA. González A, et al. Among authors: lombo f. Mol Gen Genet. 2001 Feb;264(6):827-35. doi: 10.1007/s004380000372. Mol Gen Genet. 2001. PMID: 11254130

8

Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus ATCC11891.

Méndez C, Künzel E, Lipata F, Lombó F, Cotham W, Walla M, Bearden DW, Braña AF, Salas JA, Rohr J. Méndez C, et al. Among authors: lombo f. J Nat Prod. 2002 May;65(5):779-82. doi: 10.1021/np010555n. J Nat Prod. 2002. PMID: 12027768

9

Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.

Ostash B, Rix U, Rix LL, Liu T, Lombo F, Luzhetskyy A, Gromyko O, Wang C, Braña AF, Méndez C, Salas JA, Fedorenko V, Rohr J. Ostash B, et al. Among authors: lombo f. Chem Biol. 2004 Apr;11(4):547-55. doi: 10.1016/j.chembiol.2004.03.011. Chem Biol. 2004. PMID: 15123249

10

Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891.

Lombó F, Braña AF, Salas JA, Méndez C. Lombó F, et al. Chembiochem. 2004 Sep 6;5(9):1181-7. doi: 10.1002/cbic.200400073. Chembiochem. 2004. PMID: 15368568

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