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Page 1
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay.
Heiser V, Engemann S, Bröcker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Böttcher H, Lehrach H, Wanker EE. Heiser V, et al. Among authors: boeddrich a. Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16400-6. doi: 10.1073/pnas.182426599. Epub 2002 Aug 28. Proc Natl Acad Sci U S A. 2002. PMID: 12200548 Free PMC article.
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.
Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez del Amo JM, Grüning BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Fändrich M, Frank RF, Reif B, Günther S, Walsh DM, Wanker EE. Bieschke J, et al. Among authors: boeddrich a. Nat Chem Biol. 2011 Nov 20;8(1):93-101. doi: 10.1038/nchembio.719. Nat Chem Biol. 2011. PMID: 22101602
Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity.
Stroedicke M, Bounab Y, Strempel N, Klockmeier K, Yigit S, Friedrich RP, Chaurasia G, Li S, Hesse F, Riechers SP, Russ J, Nicoletti C, Boeddrich A, Wiglenda T, Haenig C, Schnoegl S, Fournier D, Graham RK, Hayden MR, Sigrist S, Bates GP, Priller J, Andrade-Navarro MA, Futschik ME, Wanker EE. Stroedicke M, et al. Among authors: boeddrich a. Genome Res. 2015 May;25(5):701-13. doi: 10.1101/gr.182444.114. Genome Res. 2015. PMID: 25908449 Free PMC article.
18 results