Keegan AD - Search Results

1

Cutting edge: effects of an allergy-associated mutation in the human IL-4R alpha (Q576R) on human IL-4-induced signal transduction.

Wang HY, Shelburne CP, Zamorano J, Kelly AE, Ryan JJ, Keegan AD. Wang HY, et al. Among authors: keegan ad. J Immunol. 1999 Apr 15;162(8):4385-9. J Immunol. 1999. PMID: 10201973

2

Transgenic expression of insulin receptor substrate 2 in murine B cells alters the cell density-dependence of IgE production in vitro and enhances IgE production in vivo.

Kelly-Welch AE, Wang HY, Wang LM, Pierce JH, Jay G, Finkelman F, Keegan AD. Kelly-Welch AE, et al. Among authors: keegan ad. J Immunol. 2004 Mar 1;172(5):2803-10. doi: 10.4049/jimmunol.172.5.2803. J Immunol. 2004. PMID: 14978080

3

IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor alpha chain.

Wang HY, Paul WE, Keegan AD. Wang HY, et al. Among authors: keegan ad. Immunity. 1996 Feb;4(2):113-21. doi: 10.1016/s1074-7613(00)80676-7. Immunity. 1996. PMID: 8624802 Free article.

4

IL-4 protects cells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway.

Zamorano J, Wang HY, Wang LM, Pierce JH, Keegan AD. Zamorano J, et al. Among authors: keegan ad. J Immunol. 1996 Dec 1;157(11):4926-34. J Immunol. 1996. PMID: 8943397

5

The IL-4-induced tyrosine phosphorylation of the insulin receptor substrate is dependent on JAK1 expression in human fibrosarcoma cells.

Wang HY, Zamorano J, Yoerkie JL, Paul WE, Keegan AD. Wang HY, et al. Among authors: keegan ad. J Immunol. 1997 Feb 1;158(3):1037-40. J Immunol. 1997. PMID: 9013940

6

Regulation of cell growth by IL-2: role of STAT5 in protection from apoptosis but not in cell cycle progression.

Zamorano J, Wang HY, Wang R, Shi Y, Longmore GD, Keegan AD. Zamorano J, et al. Among authors: keegan ad. J Immunol. 1998 Apr 1;160(7):3502-12. J Immunol. 1998. PMID: 9531312

7

A role for the insulin-interleukin (IL)-4 receptor motif of the IL-4 receptor alpha-chain in regulating activation of the insulin receptor substrate 2 and signal transducer and activator of transcription 6 pathways. Analysis by mutagenesis.

Wang HY, Zamorano J, Keegan AD. Wang HY, et al. Among authors: keegan ad. J Biol Chem. 1998 Apr 17;273(16):9898-905. doi: 10.1074/jbc.273.16.9898. J Biol Chem. 1998. PMID: 9545332 Free article.

8

Regulation of gene expression, growth, and cell survival by IL-4: contribution of multiple signaling pathways.

Keegan AD, Zamorano J. Keegan AD, et al. Cell Res. 1998 Mar;8(1):1-13. doi: 10.1038/cr.1998.1. Cell Res. 1998. PMID: 9570012 Review.

9

Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis.

Zamorano J, Keegan AD. Zamorano J, et al. Among authors: keegan ad. J Immunol. 1998 Jul 15;161(2):859-67. J Immunol. 1998. PMID: 9670964

10

The IL-4 receptor: signaling mechanisms and biologic functions.

Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE. Nelms K, et al. Among authors: keegan ad. Annu Rev Immunol. 1999;17:701-38. doi: 10.1146/annurev.immunol.17.1.701. Annu Rev Immunol. 1999. PMID: 10358772 Review.

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