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Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels.
Pajukanta P, Terwilliger JD, Perola M, Hiekkalinna T, Nuotio I, Ellonen P, Parkkonen M, Hartiala J, Ylitalo K, Pihlajamäki J, Porkka K, Laakso M, Viikari J, Ehnholm C, Taskinen MR, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Am J Hum Genet. 1999 May;64(5):1453-63. doi: 10.1086/302365. Am J Hum Genet. 1999. PMID: 10205279 Free PMC article.
Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23.
Pajukanta P, Nuotio I, Terwilliger JD, Porkka KV, Ylitalo K, Pihlajamäki J, Suomalainen AJ, Syvänen AC, Lehtimäki T, Viikari JS, Laakso M, Taskinen MR, Ehnholm C, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Nat Genet. 1998 Apr;18(4):369-73. doi: 10.1038/ng0498-369. Nat Genet. 1998. PMID: 9537421
Different regulation of free fatty acid levels and glucose oxidation by the Trp64Arg polymorphism of the beta3-adrenergic receptor gene and the promoter variant (A-3826G) of the uncoupling protein 1 gene in familial combined hyperlipidemia.
Pihlajamäki J, Rissanen J, Valve R, Heikkinen S, Karjalainen L, Laakso M. Pihlajamäki J, et al. Among authors: laakso m. Metabolism. 1998 Nov;47(11):1397-402. doi: 10.1016/s0026-0495(98)90312-2. Metabolism. 1998. PMID: 9826220
G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia.
Pihlajamäki J, Karjalainen L, Karhapää P, Vauhkonen I, Taskinen MR, Deeb SS, Laakso M. Pihlajamäki J, et al. Among authors: laakso m. Arterioscler Thromb Vasc Biol. 2000 Jul;20(7):1789-95. doi: 10.1161/01.atv.20.7.1789. Arterioscler Thromb Vasc Biol. 2000. PMID: 10894818
The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia.
Pihlajamäki J, Miettinen R, Valve R, Karjalainen L, Mykkänen L, Kuusisto J, Deeb S, Auwerx J, Laakso M. Pihlajamäki J, et al. Among authors: laakso m. Atherosclerosis. 2000 Aug;151(2):567-74. doi: 10.1016/s0021-9150(99)00433-5. Atherosclerosis. 2000. PMID: 10924736
Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland.
Pajukanta P, Cargill M, Viitanen L, Nuotio I, Kareinen A, Perola M, Terwilliger JD, Kempas E, Daly M, Lilja H, Rioux JD, Brettin T, Viikari JS, Rönnemaa T, Laakso M, Lander ES, Peltonen L. Pajukanta P, et al. Among authors: laakso m. Am J Hum Genet. 2000 Dec;67(6):1481-93. doi: 10.1086/316902. Epub 2000 Nov 13. Am J Hum Genet. 2000. PMID: 11078477 Free PMC article.
1,395 results