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Immortalizing genes of Epstein-Barr virus.
Middleton T, Gahn TA, Martin JM, Sugden B. Middleton T, et al. Among authors: sugden b. Adv Virus Res. 1991;40:19-55. doi: 10.1016/s0065-3527(08)60276-6. Adv Virus Res. 1991. PMID: 1659776 Review.
The latent membrane protein oncoprotein resembles growth factor receptors in the properties of its turnover.
Martin J, Sugden B. Martin J, et al. Among authors: sugden b. Cell Growth Differ. 1991 Dec;2(12):653-600. Cell Growth Differ. 1991. PMID: 1667088
Kieff, Cell, 43: 831-840, 1985; V. R. Baichwal and B. Sugden, Oncogene, 2: 461-467, 1988) and, therefore, is likely to be essential for immortalization of human B-lymphocytes by Epstein-Barr virus. LMP has a short half-life in Epstein-Barr virus-infected B
Kieff, Cell, 43: 831-840, 1985; V. R. Baichwal and B. Sugden, Oncogene, 2: 461-467, 1988) and, therefore, is likely to be esse …
A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection.
Sugden B, Warren N. Sugden B, et al. J Virol. 1989 Jun;63(6):2644-9. doi: 10.1128/JVI.63.6.2644-2649.1989. J Virol. 1989. PMID: 2542577 Free PMC article.
The EBNA-1 gene therefore positively affects both viral DNA replication (J.L. Yates, N. Warren, and B. Sugden, Nature [London] 313:812-815, 1985) and viral transcription....
The EBNA-1 gene therefore positively affects both viral DNA replication (J.L. Yates, N. Warren, and B. Sugden, Nature [London] …
176 results