Vasudevan SG - Search Results

1

The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site.

Forwood JK, Brooks A, Briggs LJ, Xiao CY, Jans DA, Vasudevan SG. Forwood JK, et al. Among authors: vasudevan sg. Biochem Biophys Res Commun. 1999 Apr 21;257(3):731-7. doi: 10.1006/bbrc.1999.0370. Biochem Biophys Res Commun. 1999. PMID: 10208852

2

A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-beta and the viral helicase, NS3.

Johansson M, Brooks AJ, Jans DA, Vasudevan SG. Johansson M, et al. Among authors: vasudevan sg. J Gen Virol. 2001 Apr;82(Pt 4):735-745. doi: 10.1099/0022-1317-82-4-735. J Gen Virol. 2001. PMID: 11257177

3

Characterisation of inter- and intra-molecular interactions of the dengue virus RNA dependent RNA polymerase as potential drug targets.

Vasudevan SG, Johansson M, Brooks AJ, Llewellyn LE, Jans DA. Vasudevan SG, et al. Farmaco. 2001 Jan-Feb;56(1-2):33-6. doi: 10.1016/s0014-827x(01)01014-x. Farmaco. 2001. PMID: 11347963 Review.

4

The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals.

Brooks AJ, Johansson M, John AV, Xu Y, Jans DA, Vasudevan SG. Brooks AJ, et al. Among authors: vasudevan sg. J Biol Chem. 2002 Sep 27;277(39):36399-407. doi: 10.1074/jbc.M204977200. Epub 2002 Jun 24. J Biol Chem. 2002. PMID: 12105224 Free article.

5

Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.

Pryor MJ, Rawlinson SM, Butcher RE, Barton CL, Waterhouse TA, Vasudevan SG, Bardin PG, Wright PJ, Jans DA, Davidson AD. Pryor MJ, et al. Among authors: vasudevan sg. Traffic. 2007 Jul;8(7):795-807. doi: 10.1111/j.1600-0854.2007.00579.x. Epub 2007 May 30. Traffic. 2007. PMID: 17537211 Free article.

6

Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.

Tay MY, Fraser JE, Chan WK, Moreland NJ, Rathore AP, Wang C, Vasudevan SG, Jans DA. Tay MY, et al. Among authors: vasudevan sg. Antiviral Res. 2013 Sep;99(3):301-6. doi: 10.1016/j.antiviral.2013.06.002. Epub 2013 Jun 14. Antiviral Res. 2013. PMID: 23769930

7

Interferon-mediated ISG15 conjugation restricts dengue virus 2 replication.

Hishiki T, Han Q, Arimoto K, Shimotohno K, Igarashi T, Vasudevan SG, Suzuki Y, Yamamoto N. Hishiki T, et al. Among authors: vasudevan sg. Biochem Biophys Res Commun. 2014 May 23;448(1):95-100. doi: 10.1016/j.bbrc.2014.04.081. Epub 2014 Apr 21. Biochem Biophys Res Commun. 2014. PMID: 24769207

8

A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

Fraser JE, Watanabe S, Wang C, Chan WK, Maher B, Lopez-Denman A, Hick C, Wagstaff KM, Mackenzie JM, Sexton PM, Vasudevan SG, Jans DA. Fraser JE, et al. Among authors: vasudevan sg. J Infect Dis. 2014 Dec 1;210(11):1780-91. doi: 10.1093/infdis/jiu319. Epub 2014 Jun 5. J Infect Dis. 2014. PMID: 24903662

9

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.

Tay MY, Saw WG, Zhao Y, Chan KW, Singh D, Chong Y, Forwood JK, Ooi EE, Grüber G, Lescar J, Luo D, Vasudevan SG. Tay MY, et al. Among authors: vasudevan sg. J Biol Chem. 2015 Jan 23;290(4):2379-94. doi: 10.1074/jbc.M114.607341. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488659 Free PMC article.

10

Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R-like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells.

Fraser JE, Wang C, Chan KW, Vasudevan SG, Jans DA. Fraser JE, et al. Among authors: vasudevan sg. Antiviral Res. 2016 Jun;130:1-6. doi: 10.1016/j.antiviral.2016.03.006. Epub 2016 Mar 8. Antiviral Res. 2016. PMID: 26965420

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