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Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood-brain barrier and specifically reduce gene expression.
Tyler BM, Jansen K, McCormick DJ, Douglas CL, Boules M, Stewart JA, Zhao L, Lacy B, Cusack B, Fauq A, Richelson E. Tyler BM, et al. Among authors: douglas cl. Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7053-8. doi: 10.1073/pnas.96.12.7053. Proc Natl Acad Sci U S A. 1999. PMID: 10359837 Free PMC article.
Accelerated evolution of oligodendrocytes in the human brain.
Berto S, Mendizabal I, Usui N, Toriumi K, Chatterjee P, Douglas C, Tamminga CA, Preuss TM, Yi SV, Konopka G. Berto S, et al. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24334-24342. doi: 10.1073/pnas.1907982116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712436 Free PMC article.
Cell type-specific epigenetic links to schizophrenia risk in the brain.
Mendizabal I, Berto S, Usui N, Toriumi K, Chatterjee P, Douglas C, Huh I, Jeong H, Layman T, Tamminga CA, Preuss TM, Konopka G, Yi SV. Mendizabal I, et al. Genome Biol. 2019 Jul 9;20(1):135. doi: 10.1186/s13059-019-1747-7. Genome Biol. 2019. PMID: 31288836 Free PMC article.
Evolution of DNA methylation in the human brain.
Jeong H, Mendizabal I, Berto S, Chatterjee P, Layman T, Usui N, Toriumi K, Douglas C, Singh D, Huh I, Preuss TM, Konopka G, Yi SV. Jeong H, et al. Nat Commun. 2021 Apr 1;12(1):2021. doi: 10.1038/s41467-021-21917-7. Nat Commun. 2021. PMID: 33795684 Free PMC article.
Novel transcriptional networks regulated by CLOCK in human neurons.
Fontenot MR, Berto S, Liu Y, Werthmann G, Douglas C, Usui N, Gleason K, Tamminga CA, Takahashi JS, Konopka G. Fontenot MR, et al. Genes Dev. 2017 Nov 1;31(21):2121-2135. doi: 10.1101/gad.305813.117. Epub 2017 Dec 1. Genes Dev. 2017. PMID: 29196536 Free PMC article.
28 results