Roovers RC - Search Results

1

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.

de Haard HJ, van Neer N, Reurs A, Hufton SE, Roovers RC, Henderikx P, de Bruïne AP, Arends JW, Hoogenboom HR. de Haard HJ, et al. Among authors: roovers rc. J Biol Chem. 1999 Jun 25;274(26):18218-30. doi: 10.1074/jbc.274.26.18218. J Biol Chem. 1999. PMID: 10373423 Free article.

2

Antibody phage display technology and its applications.

Hoogenboom HR, de Bruïne AP, Hufton SE, Hoet RM, Arends JW, Roovers RC. Hoogenboom HR, et al. Among authors: roovers rc. Immunotechnology. 1998 Jun;4(1):1-20. doi: 10.1016/s1380-2933(98)00007-4. Immunotechnology. 1998. PMID: 9661810 Review.

3

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

Roovers RC, Henderikx P, Helfrich W, van der Linden E, Reurs A, de Bruïne AP, Arends JW, de Leij L, Hoogenboom HR. Roovers RC, et al. Br J Cancer. 1998 Dec;78(11):1407-16. doi: 10.1038/bjc.1998.700. Br J Cancer. 1998. PMID: 9836471 Free PMC article.

4

Model systems to study the parameters determining the success of phage antibody selections on complex antigens.

Mutuberria R, Hoogenboom HR, van der Linden E, de Bruïne AP, Roovers RC. Mutuberria R, et al. Among authors: roovers rc. J Immunol Methods. 1999 Dec 10;231(1-2):65-81. doi: 10.1016/s0022-1759(99)00141-6. J Immunol Methods. 1999. PMID: 10648928

5

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.

Beiboer SH, Reurs A, Roovers RC, Arends JW, Whitelegg NR, Rees AR, Hoogenboom HR. Beiboer SH, et al. Among authors: roovers rc. J Mol Biol. 2000 Feb 25;296(3):833-49. doi: 10.1006/jmbi.2000.3512. J Mol Biol. 2000. PMID: 10677285

6

In vitro characterisation of a monovalent and bivalent form of a fully human anti Ep-CAM phage antibody.

Roovers RC, van der Linden E, de Bruïne AP, Arends JW, Hoogenboom HR. Roovers RC, et al. Cancer Immunol Immunother. 2001 Mar;50(1):51-9. doi: 10.1007/s002620000160. Cancer Immunol Immunother. 2001. PMID: 11315510 Free PMC article.

7

Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning.

Klimka A, Matthey B, Roovers RC, Barth S, Arends JW, Engert A, Hoogenboom HR. Klimka A, et al. Among authors: roovers rc. Br J Cancer. 2000 Jul;83(2):252-60. doi: 10.1054/bjoc.2000.1226. Br J Cancer. 2000. PMID: 10901379 Free PMC article.

8

Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma.

Roovers RC, van der Linden E, de Bruïne AP, Arends JW, Hoogenboom HR. Roovers RC, et al. Eur J Cancer. 2001 Mar;37(4):542-9. doi: 10.1016/s0959-8049(00)00432-9. Eur J Cancer. 2001. PMID: 11267865

9

Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display.

Roovers RC, van der Linden E, Zijlema H, de Bruïne A, Arends JW, Hoogenboom HR. Roovers RC, et al. Int J Cancer. 2001 Sep;93(6):832-40. doi: 10.1002/ijc.1382. Int J Cancer. 2001. PMID: 11519045

10

Construction and characterization of a bispecific diabody for retargeting T cells to human carcinomas.

Helfrich W, Kroesen BJ, Roovers RC, Westers L, Molema G, Hoogenboom HR, de Leij L. Helfrich W, et al. Among authors: roovers rc. Int J Cancer. 1998 Apr 13;76(2):232-9. doi: 10.1002/(sici)1097-0215(19980413)76:2<232::aid-ijc11>3.0.co;2-e. Int J Cancer. 1998. PMID: 9537586

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