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Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V, Fan H, Abruzzo G, Flattery A, Gill C, Chrebet G, Parent SA, Kurtz M, Teppler H, Douglas CM, Perlin DS. Park S, et al. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73. doi: 10.1128/AAC.49.8.3264-3273.2005. Antimicrob Agents Chemother. 2005. PMID: 16048935 Free PMC article. Clinical Trial.
A recombinant 63-kDa form of Bacillus anthracis protective antigen produced in the yeast Saccharomyces cerevisiae provides protection in rabbit and primate inhalational challenge models of anthrax infection.
Hepler RW, Kelly R, McNeely TB, Fan H, Losada MC, George HA, Woods A, Cope LD, Bansal A, Cook JC, Zang G, Cohen SL, Wei X, Keller PM, Leffel E, Joyce JG, Pitt L, Schultz LD, Jansen KU, Kurtz M. Hepler RW, et al. Vaccine. 2006 Mar 6;24(10):1501-14. doi: 10.1016/j.vaccine.2005.10.018. Epub 2005 Oct 21. Vaccine. 2006. PMID: 16271808
66 results