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Page 1
Identification of pharmacokinetically stable 3, 10-dibromo-8-chlorobenzocycloheptapyridine farnesyl protein transferase inhibitors with potent enzyme and cellular activities.
Taveras AG, Deskus J, Chao J, Vaccaro CJ, Njoroge FG, Vibulbhan B, Pinto P, Remiszewski S, del Rosario J, Doll RJ, Alvarez C, Lalwani T, Mallams AK, Rossman RR, Afonso A, Girijavallabhan VM, Ganguly AK, Pramanik B, Heimark L, Bishop WR, Wang L, Kirschmeier P, James L, Carr D, Liu M, et al. Taveras AG, et al. Among authors: del rosario j. J Med Chem. 1999 Jul 15;42(14):2651-61. doi: 10.1021/jm990059k. J Med Chem. 1999. PMID: 10411485
Highly Regioselective Nitration Reactions Provide a Versatile Method of Functionalizing Benzocycloheptapyridine Tricyclic Ring Systems: Application toward Preparation of Nanomolar Inhibitors of Farnesyl Protein Transferase.
Njoroge FG, Vibulbhan B, Pinto P, Chan TM, Osterman R, Remiszewski S, Del Rosario J, Doll R, Girijavallabhan V, Ganguly AK. Njoroge FG, et al. Among authors: del rosario j. J Org Chem. 1998 Feb 6;63(3):445-451. doi: 10.1021/jo971100z. J Org Chem. 1998. PMID: 11672031
Detection and structural characterization of ras oncoprotein-inhibitors complexes by electrospray mass spectrometry.
Ganguly AK, Pramanik BN, Huang EC, Liberles S, Heimark L, Liu YH, Tsarbopoulos A, Doll RJ, Taveras AG, Remiszewski S, Snow ME, Wang YS, Vibulbhan B, Cesarz D, Brown JE, del Rosario J, James L, Kirschmeier P, Girijavallabhan V. Ganguly AK, et al. Among authors: del rosario j. Bioorg Med Chem. 1997 May;5(5):817-20. doi: 10.1016/s0968-0896(97)00021-7. Bioorg Med Chem. 1997. PMID: 9208093
(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5, 6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamid e (SCH-66336): a very potent farnesyl protein transferase inhibitor as a novel antitumor agent.
Njoroge FG, Taveras AG, Kelly J, Remiszewski S, Mallams AK, Wolin R, Afonso A, Cooper AB, Rane DF, Liu YT, Wong J, Vibulbhan B, Pinto P, Deskus J, Alvarez CS, del Rosario J, Connolly M, Wang J, Desai J, Rossman RR, Bishop WR, Patton R, Wang L, Kirschmeier P, Ganguly AK, et al. Njoroge FG, et al. Among authors: del rosario j. J Med Chem. 1998 Nov 19;41(24):4890-902. doi: 10.1021/jm980462b. J Med Chem. 1998. PMID: 9822558
Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships.
Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Strickland CL, et al. Among authors: del rosario j. J Med Chem. 1999 Jun 17;42(12):2125-35. doi: 10.1021/jm990030g. J Med Chem. 1999. PMID: 10377218
Ras oncoprotein inhibitors: the discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex.
Taveras AG, Remiszewski SW, Doll RJ, Cesarz D, Huang EC, Kirschmeier P, Pramanik BN, Snow ME, Wang YS, del Rosario JD, Vibulbhan B, Bauer BB, Brown JE, Carr D, Catino J, Evans CA, Girijavallabhan V, Heimark L, James L, Liberles S, Nash C, Perkins L, Senior MM, Tsarbopoulos A, Webber SE, et al. Taveras AG, et al. Among authors: del rosario jd. Bioorg Med Chem. 1997 Jan;5(1):125-33. doi: 10.1016/s0968-0896(96)00202-7. Bioorg Med Chem. 1997. PMID: 9043664
Interaction of a novel GDP exchange inhibitor with the Ras protein.
Ganguly AK, Wang YS, Pramanik BN, Doll RJ, Snow ME, Taveras AG, Remiszewski S, Cesarz D, del Rosario J, Vibulbhan B, Brown JE, Kirschmeier P, Huang EC, Heimark L, Tsarbopoulos A, Girijavallabhan VM, Aust RM, Brown EL, DeLisle DM, Fuhrman SA, Hendrickson TF, Kissinger CR, Love RA, Sisson WA, Webber SE, et al. Ganguly AK, et al. Among authors: del rosario j. Biochemistry. 1998 Nov 10;37(45):15631-7. doi: 10.1021/bi9805691. Biochemistry. 1998. PMID: 9843367
Ultrathin Boron Growth onto Nanodiamond Surfaces via Electrophilic Boron Precursors.
Govindaraju K, Supreme T, Labunsky DN, Martin N, Del Rosario JM, Washington A, Uwadiale EO, Adjei S 2nd, Ladjadj S, Melendrez CV, Lee SJ, Altoe MV, Green A, Riano S, Sainio S, Nordlund D, Wolcott A. Govindaraju K, et al. Among authors: del rosario jm. Nanomaterials (Basel). 2024 Jul 29;14(15):1274. doi: 10.3390/nano14151274. Nanomaterials (Basel). 2024. PMID: 39120380 Free PMC article.
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia.
Bhuiyan SA, Xu M, Yang L, Semizoglou E, Bhatia P, Pantaleo KI, Tochitsky I, Jain A, Erdogan B, Blair S, Cat V, Mwirigi JM, Sankaranarayanan I, Tavares-Ferreira D, Green U, McIlvried LA, Copits BA, Bertels Z, Del Rosario JS, Widman AJ, Slivicki RA, Yi J, Sharif-Naeini R, Woolf CJ, Lennerz JK, Whited JL, Price TJ, Robert W Gereau Iv, Renthal W. Bhuiyan SA, et al. Among authors: del rosario js. Sci Adv. 2024 Jun 21;10(25):eadj9173. doi: 10.1126/sciadv.adj9173. Epub 2024 Jun 21. Sci Adv. 2024. PMID: 38905344 Free article.
Pediatric COVID-19 Response in the Philippines.
Del Rosario JJD. Del Rosario JJD. Acta Med Philipp. 2024 Apr 30;58(7):10-11. doi: 10.47895/amp.v58i7.10249. eCollection 2024. Acta Med Philipp. 2024. PMID: 38882909 Free PMC article. No abstract available.
111 results