Enhanced protein thermostability by Ala-->Aib replacement.
De Filippis V, De Antoni F, Frigo M, Polverino de Laureto P, Fontana A.
De Filippis V, et al. Among authors: fontana a.
Biochemistry. 1998 Feb 10;37(6):1686-96. doi: 10.1021/bi971937o.
Biochemistry. 1998.
PMID: 9484240
The Aib analogs of fragment 255-316 were prepared by a semisynthetic approach in which the natural fragment 255-316 was coupled to synthetic analogs of peptide 303-316 using V8-protease in 50% (v/v) aqueous glycerol [De Filippis, V., and Fontana, A. (1990) In …
The Aib analogs of fragment 255-316 were prepared by a semisynthetic approach in which the natural fragment 255-316 was coupled to sy …