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Deficiency of lymph node-resident dendritic cells (DCs) and dysregulation of DC chemoattractants in a malnourished mouse model of Leishmania donovani infection.
Ibrahim MK, Barnes JL, Osorio EY, Anstead GM, Jimenez F, Osterholzer JJ, Travi BL, Ahuja SS, White AC Jr, Melby PC. Ibrahim MK, et al. Among authors: ahuja ss. Infect Immun. 2014 Aug;82(8):3098-112. doi: 10.1128/IAI.01778-14. Epub 2014 May 12. Infect Immun. 2014. PMID: 24818662 Free PMC article.
CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation.
Sato N, Ahuja SK, Quinones M, Kostecki V, Reddick RL, Melby PC, Kuziel WA, Ahuja SS. Sato N, et al. Among authors: ahuja sk, ahuja ss. J Exp Med. 2000 Jul 17;192(2):205-18. doi: 10.1084/jem.192.2.205. J Exp Med. 2000. PMID: 10899907 Free PMC article.
75 results