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The design of potent, selective, non-covalent, peptide thrombin inhibitors utilizing imidazole as a S1 binding element.
Bioorg Med Chem Lett. 1999 Sep 20;9(18):2767-72. doi: 10.1016/s0960-894x(99)00459-x.
Bioorg Med Chem Lett. 1999.
PMID: 10509932
How to improve R&D productivity: the pharmaceutical industry's grand challenge.
Paul SM, Mytelka DS, Dunwiddie CT, Persinger CC, Munos BH, Lindborg SR, Schacht AL.
Paul SM, et al. Among authors: schacht al.
Nat Rev Drug Discov. 2010 Mar;9(3):203-14. doi: 10.1038/nrd3078. Epub 2010 Feb 19.
Nat Rev Drug Discov. 2010.
PMID: 20168317
Review.
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Effect of Different Doses of Galcanezumab vs Placebo for Episodic Migraine Prevention: A Randomized Clinical Trial.
Skljarevski V, Oakes TM, Zhang Q, Ferguson MB, Martinez J, Camporeale A, Johnson KW, Shan Q, Carter J, Schacht A, Goadsby PJ, Dodick DW.
Skljarevski V, et al.
JAMA Neurol. 2018 Feb 1;75(2):187-193. doi: 10.1001/jamaneurol.2017.3859.
JAMA Neurol. 2018.
PMID: 29255900
Free PMC article.
Clinical Trial.
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Functional glycoproteomics by integrated network assembly and partitioning.
Griffin ME, Thompson JW, Xiao Y, Sweredoski MJ, Aksenfeld RB, Jensen EH, Koldobskaya Y, Schacht AL, Kim TD, Choudhry P, Lomenick B, Garbis SD, Moradian A, Hsieh-Wilson LC.
Griffin ME, et al. Among authors: schacht al.
bioRxiv [Preprint]. 2023 Jun 14:2023.06.13.541482. doi: 10.1101/2023.06.13.541482.
bioRxiv. 2023.
PMID: 37398272
Free PMC article.
Preprint.
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