Cordova BC - Search Results

1

Synthesis and evaluation of analogs of Efavirenz (SUSTIVA) as HIV-1 reverse transcriptase inhibitors.

Patel M, Ko SS, McHugh RJ Jr, Markwalder JA, Srivastava AS, Cordova BC, Klabe RM, Erickson-Viitanen S, Trainor GL, Seitz SP. Patel M, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2805-10. doi: 10.1016/s0960-894x(99)00486-2. Bioorg Med Chem Lett. 1999. PMID: 10522695

2

Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors.

Kaltenbach RF 3rd, Patel M, Waltermire RE, Harris GD, Stone BR, Klabe RM, Garber S, Bacheler LT, Cordova BC, Logue K, Wright MR, Erickson-Viitanen S, Trainor GL. Kaltenbach RF 3rd, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 2003 Feb 24;13(4):605-8. doi: 10.1016/s0960-894x(02)01064-8. Bioorg Med Chem Lett. 2003. PMID: 12639540

3

Improved P1/P1' substituents for cyclic urea based HIV-1 protease inhibitors: synthesis, structure-activity relationship, and X-ray crystal structure analysis.

Nugiel DA, Jacobs K, Cornelius L, Chang CH, Jadhav PK, Holler ER, Klabe RM, Bacheler LT, Cordova B, Garber S, Reid C, Logue KA, Gorey-Feret LJ, Lam GN, Erickson-Viitanen S, Seitz SP. Nugiel DA, et al. J Med Chem. 1997 May 9;40(10):1465-74. doi: 10.1021/jm960839i. J Med Chem. 1997. PMID: 9154969

4

Design, synthesis, and evaluation of tetrahydropyrimidinones as an example of a general approach to nonpeptide HIV protease inhibitors.

De Lucca GV, Liang J, Aldrich PE, Calabrese J, Cordova B, Klabe RM, Rayner MM, Chang CH. De Lucca GV, et al. J Med Chem. 1997 May 23;40(11):1707-9. doi: 10.1021/jm970081i. J Med Chem. 1997. PMID: 9171880

5

Nonsymmetric P2/P2' cyclic urea HIV protease inhibitors. Structure-activity relationship, bioavailability, and resistance profile of monoindazole-substituted P2 analogues.

De Lucca GV, Kim UT, Liang J, Cordova B, Klabe RM, Garber S, Bacheler LT, Lam GN, Wright MR, Logue KA, Erickson-Viitanen S, Ko SS, Trainor GL. De Lucca GV, et al. J Med Chem. 1998 Jun 18;41(13):2411-23. doi: 10.1021/jm980103g. J Med Chem. 1998. PMID: 9632373

6

Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors.

Rodgers JD, Lam PY, Johnson BL, Wang H, Li R, Ru Y, Ko SS, Seitz SP, Trainor GL, Anderson PS, Klabe RM, Bacheler LT, Cordova B, Garber S, Reid C, Wright MR, Chang CH, Erickson-Viitanen S. Rodgers JD, et al. Chem Biol. 1998 Oct;5(10):597-608. doi: 10.1016/s1074-5521(98)90117-x. Chem Biol. 1998. PMID: 9818151

7

Potent cyclic urea HIV protease inhibitors with 3-aminoindazole P2/P2' groups.

Rodgers JD, Johnson BL, Wang H, Erickson-Viitanen S, Klabe RM, Bacheler L, Cordova BC, Chang CH. Rodgers JD, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 1998 Apr 7;8(7):715-20. doi: 10.1016/s0960-894x(98)00118-8. Bioorg Med Chem Lett. 1998. PMID: 9871528

8

The synthesis and evaluation of cyclic ureas as HIV protease inhibitors: modifications of the P1/P1' residues.

Patel M, Bacheler LT, Rayner MM, Cordova BC, Klabe RM, Erickson-Viitanen S, Seitz SP. Patel M, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 1998 Apr 7;8(7):823-8. doi: 10.1016/s0960-894x(98)00119-x. Bioorg Med Chem Lett. 1998. PMID: 9871548

9

The synthesis of symmetrical and unsymmetrical P1/P1' cyclic ureas as HIV protease inhibitors.

Patel M, Kaltenbach RF 3rd, Nugiel DA, McHugh RJ Jr, Jadhav PK, Bacheler LT, Cordova BC, Klabe RM, Erickson-Viitanen S, Garber S, Reid C, Seitz SP. Patel M, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 1998 May 5;8(9):1077-82. doi: 10.1016/s0960-894x(98)00175-9. Bioorg Med Chem Lett. 1998. PMID: 9871711

10

Increased antiviral activity of cyclic urea HIV protease inhibitors by modifying the P1/P1' substituents.

Kaltenbach RF 3rd, Klabe RM, Cordova BC, Seitz SP. Kaltenbach RF 3rd, et al. Among authors: cordova bc. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2259-62. doi: 10.1016/s0960-894x(99)00367-4. Bioorg Med Chem Lett. 1999. PMID: 10465557

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