Yan Y - Search Results

1

Purification, solution properties and crystallization of SIV integrase containing a continuous core and C-terminal domain.

Li Y, Yan Y, Zugay-Murphy J, Xu B, Cole JL, Witmer M, Felock P, Wolfe A, Hazuda D, Sardana MK, Chen Z, Kuo LC, Sardana VV. Li Y, et al. Among authors: yan y. Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1906-10. doi: 10.1107/s0907444999009610. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10531491

2

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.

Chen Z, Yan Y, Munshi S, Li Y, Zugay-Murphy J, Xu B, Witmer M, Felock P, Wolfe A, Sardana V, Emini EA, Hazuda D, Kuo LC. Chen Z, et al. Among authors: yan y. J Mol Biol. 2000 Feb 18;296(2):521-33. doi: 10.1006/jmbi.1999.3451. J Mol Biol. 2000. PMID: 10669606

3

Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: a 2.2 A resolution structure in a hexagonal crystal form.

Yan Y, Li Y, Munshi S, Sardana V, Cole JL, Sardana M, Steinkuehler C, Tomei L, De Francesco R, Kuo LC, Chen Z. Yan Y, et al. Protein Sci. 1998 Apr;7(4):837-47. doi: 10.1002/pro.5560070402. Protein Sci. 1998. PMID: 9568891 Free PMC article.

4

Crystallization and preliminary X-ray analysis of the Escherichia coli UDP-MurNAc-tripeptide D-alanyl-D-alanine-adding enzyme (MurF).

Yan Y, Munshi S, Li Y, Pryor KA, Marsilio F, Leiting B. Yan Y, et al. Acta Crystallogr D Biol Crystallogr. 1999 Dec;55(Pt 12):2033-4. doi: 10.1107/s0907444999011786. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10666581

5

An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.

Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC. Munshi S, et al. Among authors: yan y. Acta Crystallogr D Biol Crystallogr. 2000 Apr;56(Pt 4):381-8. doi: 10.1107/s0907444900000469. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10739910

6

Inhibition of a mitotic motor protein: where, how, and conformational consequences.

Yan Y, Sardana V, Xu B, Homnick C, Halczenko W, Buser CA, Schaber M, Hartman GD, Huber HE, Kuo LC. Yan Y, et al. J Mol Biol. 2004 Jan 9;335(2):547-54. doi: 10.1016/j.jmb.2003.10.074. J Mol Biol. 2004. PMID: 14672662

7

Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.

Su HP, Yan Y, Prasad GS, Smith RF, Daniels CL, Abeywickrema PD, Reid JC, Loughran HM, Kornienko M, Sharma S, Grobler JA, Xu B, Sardana V, Allison TJ, Williams PD, Darke PL, Hazuda DJ, Munshi S. Su HP, et al. Among authors: yan y. J Virol. 2010 Aug;84(15):7625-33. doi: 10.1128/JVI.00353-10. Epub 2010 May 19. J Virol. 2010. PMID: 20484498 Free PMC article.

8

Small, low nanomolar, noncovalent thrombin inhibitors lacking a group to fill the 'distal binding pocket'.

Sanderson PE, Cutrona KJ, Dyer DL, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, Yan Y. Sanderson PE, et al. Among authors: yan y. Bioorg Med Chem Lett. 2003 Jan 20;13(2):161-4. doi: 10.1016/s0960-894x(02)00946-0. Bioorg Med Chem Lett. 2003. PMID: 12482415

9

Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution.

Yan Y, Munshi S, Leiting B, Anderson MS, Chrzas J, Chen Z. Yan Y, et al. J Mol Biol. 2000 Dec 1;304(3):435-45. doi: 10.1006/jmbi.2000.4215. J Mol Biol. 2000. PMID: 11090285

10

Development of thioquinazolinones, allosteric Chk1 kinase inhibitors.

Converso A, Hartingh T, Garbaccio RM, Tasber E, Rickert K, Fraley ME, Yan Y, Kreatsoulas C, Stirdivant S, Drakas B, Walsh ES, Hamilton K, Buser CA, Mao X, Abrams MT, Beck SC, Tao W, Lobell R, Sepp-Lorenzino L, Zugay-Murphy J, Sardana V, Munshi SK, Jezequel-Sur SM, Zuck PD, Hartman GD. Converso A, et al. Among authors: yan y. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1240-4. doi: 10.1016/j.bmcl.2008.12.076. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19155174

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