Witte L - Search Results

1

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors.

Prewett M, Huber J, Li Y, Santiago A, O'Connor W, King K, Overholser J, Hooper A, Pytowski B, Witte L, Bohlen P, Hicklin DJ. Prewett M, et al. Among authors: witte l. Cancer Res. 1999 Oct 15;59(20):5209-18. Cancer Res. 1999. PMID: 10537299

2

Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: witte l. Int J Cancer. 2002 Jan 20;97(3):393-9. doi: 10.1002/ijc.1634. Int J Cancer. 2002. PMID: 11774295

3

Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics.

Zhu Z, Bohlen P, Witte L. Zhu Z, et al. Among authors: witte l. Curr Cancer Drug Targets. 2002 Jun;2(2):135-56. doi: 10.2174/1568009023333881. Curr Cancer Drug Targets. 2002. PMID: 12188915 Review.

4

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL. Burtrum D, et al. Among authors: witte l. Cancer Res. 2003 Dec 15;63(24):8912-21. Cancer Res. 2003. PMID: 14695208

5

Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.

Zhang H, Li Y, Li H, Bassi R, Jimenez X, Witte L, Bohlen P, Hicklin D, Zhu Z. Zhang H, et al. Among authors: witte l. Leuk Lymphoma. 2004 Sep;45(9):1887-97. doi: 10.1080/10428190410001712225. Leuk Lymphoma. 2004. PMID: 15223651

6

Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody.

Pytowski B, Goldman J, Persaud K, Wu Y, Witte L, Hicklin DJ, Skobe M, Boardman KC, Swartz MA. Pytowski B, et al. Among authors: witte l. J Natl Cancer Inst. 2005 Jan 5;97(1):14-21. doi: 10.1093/jnci/dji003. J Natl Cancer Inst. 2005. PMID: 15632376

7

Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target.

Loizos N, Xu Y, Huber J, Liu M, Lu D, Finnerty B, Rolser R, Malikzay A, Persaud A, Corcoran E, Deevi DS, Balderes P, Bassi R, Jimenez X, Joynes CJ, Mangalampalli VR, Steiner P, Tonra JR, Wu Y, Pereira DS, Zhu Z, Ludwig DL, Hicklin DJ, Bohlen P, Witte L, Kussie P. Loizos N, et al. Among authors: witte l. Mol Cancer Ther. 2005 Mar;4(3):369-79. doi: 10.1158/1535-7163.MCT-04-0114. Mol Cancer Ther. 2005. PMID: 15767546

8

The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma.

Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. Wu Y, et al. Among authors: witte l. Int J Cancer. 2006 Oct 1;119(7):1519-29. doi: 10.1002/ijc.21865. Int J Cancer. 2006. PMID: 16671089

9

Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth.

Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, Steiner P, Hicklin D, Persaud K, Tonra JR, Witte L, Alitalo K. Laakkonen P, et al. Among authors: witte l. Cancer Res. 2007 Jan 15;67(2):593-9. doi: 10.1158/0008-5472.CAN-06-3567. Cancer Res. 2007. PMID: 17234768

10

Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.

Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR. Surguladze D, et al. Among authors: witte l. Cancer Res. 2009 Jul 15;69(14):5643-7. doi: 10.1158/0008-5472.CAN-09-0487. Epub 2009 Jul 7. Cancer Res. 2009. PMID: 19584274

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