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Phase I and pharmacokinetic study of a daily times 5 short intravenous infusion schedule of 9-aminocamptothecin in a colloidal dispersion formulation in patients with advanced solid tumors.
Herben VM, van Gijn R, Schellens JH, Schot M, Lieverst J, Hillebrand MJ, Schoemaker NE, Porro MG, Beijnen JH, ten Bokkel Huinink WW. Herben VM, et al. J Clin Oncol. 1999 Jun;17(6):1906-14. doi: 10.1200/JCO.1999.17.6.1906. J Clin Oncol. 1999. PMID: 10561232 Clinical Trial.
High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.
van Gijn R, Herben VM, Hillebrand MJ, ten Bokkel Huinink WW, Bult A, Beijnen JH. van Gijn R, et al. Among authors: herben vm. J Pharm Biomed Anal. 1998 Sep;17(8):1257-65. doi: 10.1016/s0731-7085(97)00257-4. J Pharm Biomed Anal. 1998. PMID: 9800645
Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer.
Herben VM, Panday VR, Richel DJ, Schellens JH, van der Vange N, Rosing H, Beusenberg FD, Hearn S, Doyle E, Beijnen JH, ten Bokkel Huinink WW. Herben VM, et al. J Clin Oncol. 1999 Mar;17(3):747-55. doi: 10.1200/JCO.1999.17.3.747. J Clin Oncol. 1999. PMID: 10071262 Clinical Trial.
Clinical pharmacokinetics of topotecan.
Herben VM, ten Bokkel Huinink WW, Beijnen JH. Herben VM, et al. Clin Pharmacokinet. 1996 Aug;31(2):85-102. doi: 10.2165/00003088-199631020-00001. Clin Pharmacokinet. 1996. PMID: 8853931 Review.
17 results