Lan NC - Search Results

1

Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids.

Vanover KE, Edgar DM, Seidel WF, Hogenkamp DJ, Fick DB, Lan NC, Gee KW, Carter RB. Vanover KE, et al. Among authors: lan nc. J Pharmacol Exp Ther. 1999 Dec;291(3):1317-23. J Pharmacol Exp Ther. 1999. PMID: 10565857

2

Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.

Carter RB, Wood PL, Wieland S, Hawkinson JE, Belelli D, Lambert JJ, White HS, Wolf HH, Mirsadeghi S, Tahir SH, Bolger MB, Lan NC, Gee KW. Carter RB, et al. Among authors: lan nc. J Pharmacol Exp Ther. 1997 Mar;280(3):1284-95. J Pharmacol Exp Ther. 1997. PMID: 9067315

3

Partial agonism by 3alpha,21-dihydroxy-5beta-pregnan-20-one at the gamma-aminobutyric acidA receptor neurosteroid site.

Xue BG, Whittemore ER, Park CH, Woodward RM, Lan NC, Gee KW. Xue BG, et al. Among authors: lan nc. J Pharmacol Exp Ther. 1997 Jun;281(3):1095-101. J Pharmacol Exp Ther. 1997. PMID: 9190841

4

CCD-3693: an orally bioavailable analog of the endogenous neuroactive steroid, pregnanolone, demonstrates potent sedative hypnotic actions in the rat.

Edgar DM, Seidel WF, Gee KW, Lan NC, Field G, Xia H, Hawkinson JE, Wieland S, Carter RB, Wood PL. Edgar DM, et al. Among authors: lan nc. J Pharmacol Exp Ther. 1997 Jul;282(1):420-9. J Pharmacol Exp Ther. 1997. PMID: 9223583

5

Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.

Hawkinson JE, Acosta-Burruel M, Yang KC, Hogenkamp DJ, Chen JS, Lan NC, Drewe JA, Whittemore ER, Woodward RM, Carter RB, Upasani RB. Hawkinson JE, et al. Among authors: lan nc. J Pharmacol Exp Ther. 1998 Oct;287(1):198-207. J Pharmacol Exp Ther. 1998. PMID: 9765338

6

Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol.

Vanover KE, Suruki M, Robledo S, Huber M, Wieland S, Lan NC, Gee KW, Wood PL, Carter RB. Vanover KE, et al. Among authors: lan nc. Psychopharmacology (Berl). 1999 Jan;141(1):77-82. doi: 10.1007/s002130050809. Psychopharmacology (Berl). 1999. PMID: 9952068

7

Characterization of the anxiolytic properties of a novel neuroactive steroid, Co 2-6749 (GMA-839; WAY-141839; 3alpha, 21-dihydroxy-3beta-trifluoromethyl-19-nor-5beta-pregnan-20-one), a selective modulator of gamma-aminobutyric acid(A) receptors.

Vanover KE, Rosenzweig-Lipson S, Hawkinson JE, Lan NC, Belluzzi JD, Stein L, Barrett JE, Wood PL, Carter RB. Vanover KE, et al. Among authors: lan nc. J Pharmacol Exp Ther. 2000 Oct;295(1):337-45. J Pharmacol Exp Ther. 2000. PMID: 10991999

8

Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid.

Vanover KE, Hogenkamp DJ, Lan NC, Gee KW, Carter RB. Vanover KE, et al. Among authors: lan nc. Psychopharmacology (Berl). 2001 May;155(3):285-91. doi: 10.1007/s002130100695. Psychopharmacology (Berl). 2001. PMID: 11432691

9

Gamma-aminobutyric acidA receptor complexes in rat frontal cortex and spinal cord show differential responses to steroid modulation.

Gee KW, Lan NC. Gee KW, et al. Among authors: lan nc. Mol Pharmacol. 1991 Dec;40(6):995-9. Mol Pharmacol. 1991. PMID: 1661843

10

Neuroactive steroid actions at the GABAA receptor.

Lan NC, Gee KW. Lan NC, et al. Horm Behav. 1994 Dec;28(4):537-44. doi: 10.1006/hbeh.1994.1052. Horm Behav. 1994. PMID: 7729823 Review.

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