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Discovery of novel non-peptide CCR1 receptor antagonists.
Ng HP, May K, Bauman JG, Ghannam A, Islam I, Liang M, Horuk R, Hesselgesser J, Snider RM, Perez HD, Morrissey MM. Ng HP, et al. Among authors: perez hd. J Med Chem. 1999 Nov 4;42(22):4680-94. doi: 10.1021/jm990316l. J Med Chem. 1999. PMID: 10579830
Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.
Liang M, Rosser M, Ng HP, May K, Bauman JG, Islam I, Ghannam A, Kretschmer PJ, Pu H, Dunning L, Snider RM, Morrissey MM, Hesselgesser J, Perez HD, Horuk R. Liang M, et al. Among authors: perez hd. Eur J Pharmacol. 2000 Feb 11;389(1):41-9. doi: 10.1016/s0014-2999(99)00863-8. Eur J Pharmacol. 2000. PMID: 10686294
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
Liang M, Mallari C, Rosser M, Ng HP, May K, Monahan S, Bauman JG, Islam I, Ghannam A, Buckman B, Shaw K, Wei GP, Xu W, Zhao Z, Ho E, Shen J, Oanh H, Subramanyam B, Vergona R, Taub D, Dunning L, Harvey S, Snider RM, Hesselgesser J, Morrissey MM, Perez HD. Liang M, et al. Among authors: perez hd. J Biol Chem. 2000 Jun 23;275(25):19000-8. doi: 10.1074/jbc.M001222200. J Biol Chem. 2000. PMID: 10748002 Free article.
A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.
Horuk R, Clayberger C, Krensky AM, Wang Z, Grone HJ, Weber C, Weber KS, Nelson PJ, May K, Rosser M, Dunning L, Liang M, Buckman B, Ghannam A, Ng HP, Islam I, Bauman JG, Wei GP, Monahan S, Xu W, Snider RM, Morrissey MM, Hesselgesser J, Perez HD. Horuk R, et al. Among authors: perez hd. J Biol Chem. 2001 Feb 9;276(6):4199-204. doi: 10.1074/jbc.M007457200. Epub 2000 Oct 27. J Biol Chem. 2001. PMID: 11054419 Free article.
CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.
Horuk R, Shurey S, Ng HP, May K, Bauman JG, Islam I, Ghannam A, Buckman B, Wei GP, Xu W, Liang M, Rosser M, Dunning L, Hesselgesser J, Snider RM, Morrissey MM, Perez HD, Green C. Horuk R, et al. Among authors: perez hd. Immunol Lett. 2001 Apr 2;76(3):193-201. doi: 10.1016/s0165-2478(01)00172-9. Immunol Lett. 2001. PMID: 11306147
96 results