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Blockade of the action of nitric oxide in human septic shock increases systemic vascular resistance and has detrimental effects on pulmonary function after a short infusion of methylene blue.
Weingartner R, Oliveira E, Oliveira ES, Sant'Anna UL, Oliveira RP, Azambuja LA, Friedman G. Weingartner R, et al. Among authors: azambuja la. Braz J Med Biol Res. 1999 Dec;32(12):1505-13. doi: 10.1590/s0100-879x1999001200009. Braz J Med Biol Res. 1999. PMID: 10585632 Free article. Clinical Trial.