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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.
Huber BE, Austin EA, Richards CA, Davis ST, Good SS. Huber BE, et al. Among authors: austin ea. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8302-6. doi: 10.1073/pnas.91.17.8302. Proc Natl Acad Sci U S A. 1994. PMID: 8058798 Free PMC article.
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