Spiekstra SW - Search Results

1

Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4.

Vandebriel RJ, De Jong WH, Spiekstra SW, Van Dijk M, Fluitman A, Garssen J, Van Loveren H. Vandebriel RJ, et al. Among authors: spiekstra sw. Toxicol Appl Pharmacol. 2000 Jan 15;162(2):77-85. doi: 10.1006/taap.1999.8841. Toxicol Appl Pharmacol. 2000. PMID: 10637130

2

Ranking of allergenic potency of rubber chemicals in a modified local lymph node assay.

De Jong WH, Van Och FM, Den Hartog Jager CF, Spiekstra SW, Slob W, Vandebriel RJ, Van Loveren H. De Jong WH, et al. Among authors: spiekstra sw. Toxicol Sci. 2002 Apr;66(2):226-32. doi: 10.1093/toxsci/66.2.226. Toxicol Sci. 2002. PMID: 11896289

3

Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.

De Jong WH, Tentij M, Spiekstra SW, Vandebriel RJ, Van Loveren H. De Jong WH, et al. Among authors: spiekstra sw. Toxicology. 2002 Jul 1;176(1-2):123-34. doi: 10.1016/s0300-483x(02)00131-2. Toxicology. 2002. PMID: 12062936

4

In vitro exposure effects of cyclosporin A and bis(tri-n-butyltin)oxide on lymphocyte proliferation, cytokine (receptor) mRNA expression, and cell surface marker expression in rat thymocytes and splenocytes.

Vandebriel RJ, Spiekstra SW, Hudspith BN, Meredith C, Van Loveren H. Vandebriel RJ, et al. Among authors: spiekstra sw. Toxicology. 1999 Jul 1;135(1):49-66. doi: 10.1016/s0300-483x(99)00049-9. Toxicology. 1999. PMID: 10454224

5

An epidermal equivalent assay for identification and ranking potency of contact sensitizers.

Gibbs S, Corsini E, Spiekstra SW, Galbiati V, Fuchs HW, Degeorge G, Troese M, Hayden P, Deng W, Roggen E. Gibbs S, et al. Among authors: spiekstra sw. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):529-41. doi: 10.1016/j.taap.2013.07.003. Epub 2013 Jul 19. Toxicol Appl Pharmacol. 2013. PMID: 23876969

6

Assessment of metal sensitizer potency with the reconstructed human epidermis IL-18 assay.

Gibbs S, Kosten I, Veldhuizen R, Spiekstra S, Corsini E, Roggen E, Rustemeyer T, Feilzer AJ, Kleverlaan CJ. Gibbs S, et al. Toxicology. 2018 Jan 15;393:62-72. doi: 10.1016/j.tox.2017.10.014. Epub 2017 Oct 25. Toxicology. 2018. PMID: 29079364 Free article.

7

MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure.

Kosten IJ, Spiekstra SW, de Gruijl TD, Gibbs S. Kosten IJ, et al. Among authors: spiekstra sw. Toxicol Appl Pharmacol. 2015 Aug 15;287(1):35-42. doi: 10.1016/j.taap.2015.05.017. Epub 2015 May 29. Toxicol Appl Pharmacol. 2015. PMID: 26028481 Free article.

8

Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency.

Teunis M, Corsini E, Smits M, Madsen CB, Eltze T, Ezendam J, Galbiati V, Gremmer E, Krul C, Landin A, Landsiedel R, Pieters R, Rasmussen TF, Reinders J, Roggen E, Spiekstra S, Gibbs S. Teunis M, et al. Toxicol In Vitro. 2013 Apr;27(3):1135-50. doi: 10.1016/j.tiv.2012.06.004. Epub 2012 Jun 19. Toxicol In Vitro. 2013. PMID: 22728231

9

Induction of cytokine (interleukin-1alpha and tumor necrosis factor-alpha) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure.

Spiekstra SW, Toebak MJ, Sampat-Sardjoepersad S, van Beek PJ, Boorsma DM, Stoof TJ, von Blomberg BM, Scheper RJ, Bruynzeel DP, Rustemeyer T, Gibbs S. Spiekstra SW, et al. Exp Dermatol. 2005 Feb;14(2):109-16. doi: 10.1111/j.0906-6705.2005.00226.x. Exp Dermatol. 2005. PMID: 15679580

10

International ring trial of the epidermal equivalent sensitizer potency assay: reproducibility and predictive-capacity.

Teunis MA, Spiekstra SW, Smits M, Adriaens E, Eltze T, Galbiati V, Krul C, Landsiedel R, Pieters R, Reinders J, Roggen E, Corsini E, Gibbs S. Teunis MA, et al. Among authors: spiekstra sw. ALTEX. 2014;31(3):251-68. doi: 10.14573/altex.1308021. Epub 2014 Feb 17. ALTEX. 2014. PMID: 24535238 Free article.

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