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Identification of a novel aspartic protease (Asp 2) as beta-secretase.
Hussain I, Powell D, Howlett DR, Tew DG, Meek TD, Chapman C, Gloger IS, Murphy KE, Southan CD, Ryan DM, Smith TS, Simmons DL, Walsh FS, Dingwall C, Christie G. Hussain I, et al. Among authors: walsh fs. Mol Cell Neurosci. 1999 Dec;14(6):419-27. doi: 10.1006/mcne.1999.0811. Mol Cell Neurosci. 1999. PMID: 10656250
ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
Hussain I, Powell DJ, Howlett DR, Chapman GA, Gilmour L, Murdock PR, Tew DG, Meek TD, Chapman C, Schneider K, Ratcliffe SJ, Tattersall D, Testa TT, Southan C, Ryan DM, Simmons DL, Walsh FS, Dingwall C, Christie G. Hussain I, et al. Among authors: walsh fs. Mol Cell Neurosci. 2000 Nov;16(5):609-19. doi: 10.1006/mcne.2000.0884. Mol Cell Neurosci. 2000. PMID: 11083922
Inhibitor of neurite outgrowth in humans.
Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G, Michalovich D, Simmons DL, Walsh FS. Prinjha R, et al. Among authors: walsh fs. Nature. 2000 Jan 27;403(6768):383-4. doi: 10.1038/35000287. Nature. 2000. PMID: 10667780 No abstract available.
252 results